Friday, 30 March 2018

Can you get double doses of steroids?

Further to my DNA on Steroids post below MyHeritage are continuing to roll out improvements to their offerings, not only for DNA but also, FINALLY, a pedigree view of their family tree which is has been a major shortcoming of the site for years.
A pedigree view for the DNA shared matches has been available for a while, but not for the overall tree.
It is being gradually rolled out so not everyone can see it as yet.

On the DNA front:
https://blog.myheritage.com/2018/03/new-improvements-in-the-one-to-many-chromosome-browser/
explains the latest improvements to the One to Many Chromosome browser, and the new indicator visible when you are looking at a match and seeing who else they also share DNA with.


This all being on top of some tweaks to the navigation on the still rather unwieldy match lists *
https://blog.myheritage.com/2018/03/new-easier-navigation-in-your-dna-match-list/
that allow you to jump to specific pages, increase the number of matches per page.

* which are able to be filtered and sorted by a useful range of criteria, eg filter for "has family tree" although this will still include those with only one person in their tree. MyHeritage developers have reported in Facebook comments that they are working on that - particularly those where a test is ordered, and the tree developed, separately, without the person realising they can go back to Manage DNA kits and reassign a kit to the person who is now both in the tree, and "floating" unconnected.

Monday, 12 March 2018

End of an era

Oxford Ancestors is closing down.

Read Bryan Sykes' farewell at http://www.oxfordancestors.com

He certainly stimulated my interest in DNA testing, and is how I began my genetic journey, back in 2003 - I think.

I use the wonderfully colourful picture of my "Tara" haplogroup regularly, although the details have long since been improved with a mtDNA full sequence test from FamilyTreeDNA, and supplemented by autosomal testing - all for a fraction of the price paid for this initial test.

Thank you Bryan.

Roberta Estes' blog post at DNAeXplained has a very thoughtful article about the demise of yet another DNA resource, including what you can/should do to preserve your DNA.



Saturday, 3 March 2018

DNA on steroids!

MyHeritage have come good on two more of their promises.
I'm hedging my bets about how many promises they may have made, but these two are important to me :)
(See also further improvements in later post above: http://dnasurnames.blogspot.com/2018/03/can-you-get-double-doses-of-steroids.html)

1) Chromosome browser comparisons between up to 8 kits - WITH triangulated segments identified.

Have only had a chance for a brief play to date, and like several others on assorted lists, fell into the first trap.
Why aren't the triangulations showing?
Well they do, but only if all those in the selected list triangulate, so you have to add/subtract people for the list.
Which is a bit hit or miss without more knowledge or prior downloads of the one to one comparisons introduced back in January - and where promise number 2 comes in for less miss and more hit.
OR, opening another tab with the shared match list open :)

Here's a picture of a "hit" - I'm the grey background comparing with three of my Henderson/Wight or Henderson/Millar paternal side 2nd and 3rd cousins:
Note chromosome 7 with it's border around the triangulated segments.
Click inside the border and get the popup with details.


2) Ability to download all your match and segment data.
I cannot report on what that looks like as yet, having whizzed through all my kits requesting the downloads, and been promised an email when they were ready -nothing has yet arrived, some hours later *. Suspect they'll be a bit snowed under with that one.
* update from MyHeritage, all sent so the hold up appears to be the mail system somewhere, and no, they aren't in my spam folder.

Without such an ability I strongly suspect I've been missing out on noticing interesting new matches as unlike Ancestry you cannot quickly see which kits are new and have not yet been checked.
With Ancestry you can filter by just your new matches sorted by order of relationship, ie the most interesting float to the top. There's also a sort option by date - which is less useful in general. I tend to use that only to re-find the matches I've starred recently on Ancestry.
With FamilyTreeDNA's much more compact match list display than MyHeritage the "by match date" sort there is easy to quickly scan down for the larger new matches.

Here's the announcement received from MyHeritage including the links to their blog to explain the new features:
===
We are excited to announce a major upgrade to the Chromosome Browser on MyHeritage. With this upgrade, we’ve upped our genetic genealogy game considerably to help people better understand how they are related to their DNA Matches. Together with family tree details like shared ancestral surnames and shared Smart Matches, users may be able to trace back the common ancestors who passed down shared DNA segments to them and their DNA Matches, and reconstruct the exact relationship path between themselves and DNA Matches that they find intriguing.
The initial version of the MyHeritage Chromosome Browser, released in January 2018, was a one-to-one chromosome browser. It displays DNA segments shared by you with one DNA Match.
The new One-to-Many Chromosome Browser, with its support for indicating triangulated segments, is an exciting addition to MyHeritage’s growing arsenal of useful tools for genetic genealogy. The tool is completely free.

Also new is the ability to export the list of DNA Matches, along with several other export capabilities.
Best regrads,
Daniel Horowitz
Genealogy Expert



Sunday, 21 January 2018

Onset of results

The BigY, and companion Y111 upgrade, results from the last sale are starting to roll in, so it was time to republish DNASurnames (both Haplogroup overviews and Lineage/result sections), but expect further updates as quite a few results have yet to arrive.

I've not kept full track of which ones have changed when but know there were updates in the Fairbairn and McAdie projects - still waiting on those for the Andrews, Bain, Dawe, Rowe, Sinton (from the previous sale, as it had to be re-run) surnames.

Friday, 12 January 2018

Kudos to MyHeritage

The MyHeritage Year in Review blog post of 26 Dec 2017 contained this statement:

You can count on MyHeritage DNA to continue to grow rapidly and improve in accuracy and features. We are working on a major revamp of the matching algorithms which will correct old problems, add a preliminary Chromosome Browser and put accuracy at an unprecedented high level, and this will be released in early January 2018.  

It is now 11 January 2018 and they have already come good on the promise to revamp the matching algorithms (but not as far as I can see, a Chromosome Browser - but see update below).

The problems I reported earlier, my own 2nd cousin not appearing in my matches, and the predicted 2nd cousin on Ancestry and FamilyTreeDNA that was missing on MyHeritage are both now fixed.
As has one I'd not reported to them and only discovered this afternoon - a match that wasn't real but showed as reasonably strong, (45cMs approximately, 5 segments) now shows as "not related", as suspected.
Also fixed, a predicted relationship of father/daughter now rather more accurately showing as siblings!

Support was on the ball too, sent me a message advising me the update had happened, and asking for my report on whether or not my issues had been solved.
Yes.

Update:
Within a hour or so of my posting the above the promised chromosome browser was also there, with an ability to download the segment details for that individual match.
Along with a message from MyHeritage pointing me to their blog post about the improvements:
https://blog.myheritage.com/2018/01/major-updates-and-improvements-to-myheritage-dna-matching/

The match lists have grown immensely to be far more in line with those from other companies, instead of rather sparse and suspect before the upgrade.

As I've popped in our local Genie society newsletter for our DNA group news:
MyHeritage is definitely now a major player in the genetic genealogy stakes, and should deserve more consideration than Ancestry given the Chromosome Browser.

My preferred strategy should I be starting out again now would be to:
Test FamilyFinder at FamilyTreeDNA (FTDNA) to get a sample on file there available for the more specialised tests FTDNA also offer that the other companies do not - and provide hassle free communication with matches.
Then transfer that FamilyFinder file to MyHeritage to fish in that pond too - as well as GEDMatch of course.

If you've already tested at MyHeritage, that test can be transferred to FTDNA for free
https://www.familytreedna.com/landing/atdna-landing.aspx

Read Roberta Estes' post on Ancestry/FTDNA transfers before making up your mind about transferring an Ancestry test to FTDNA (they can't go the other way):
https://dna-explained.com/2017/12/04/testing-strategy-should-i-test-at-ancestry-and-transfer-to-family-tree-dna/

Don't forget GEDmatch - that cousin you've been looking for could be on any of the sites, so you should be on as many as you can too.



Sunday, 10 December 2017

DNASurnames - Haplogroup tree update

With a set of new BigY results in from the last sale, revisions have been made to the Haplogroup trees on DNASurnames - mainly under Fairbairn and Dawe but one or two others.

Check out the Recent changes.

Please note the trees are by no means all haplogroups, just those relevant to people of interest.
They show a position on the tree, with the profiles for the haplogroups sometimes including links to eg yFull, the BigTree, Surname projects for more info.

"Children" shown on a profile page include either more recent SNPs down that branch of the tree, or a patriarch for a tester of interest's line.
Each branch is collapsible/expandable to aid showing the relevant bits of the tree.

For ease of navigation, you can click on a chart link on the profile page, or in the little blue pedigree symbol up against the name for an overview of "ancestors" and "children".

Have you bitten the bullet and upgraded a relevant person for your surname of interest to BigY?
The sale price until the end of December is $100 off, but FTDNA have thrown in an upgrade to yDNA111 from whatever yDNA markers you already have.
Coupon codes are available each week that may sometimes be valid for BigY in addition to this.
I may have some available for suitable candidates in the projects I admin, or am interested in.



Sunday, 15 October 2017

Yet another MyHeritage DNA mystery

This one is another in the category of what you can't see you DO miss, ie another example of a close match reported by, in this instance, FamilyTreeDNA, and GEDMatch, but not shown on MyHeritage.

Original tests both done on FamilyTreeDNA (May 2010 and Oct 2016), both uploaded to GEDMatch and both transferred to MyHeritage.

Actual relationship 2nd cousins.

FamilyTreeDNA:
Predicted relationship 2nd to 3rd cousin sharing a total of 144cMs, largest segment 19 cMs
Looking at only those segments over 7cMs this reduces to a total of 96 cMs over 7 segments  (including a 10cMs X chromosome match)




Chromosome Start Location End Location centiMorgans (cM) # of Matching SNPs
1 90373522 107499183 14.1 4500
2 50979064 71469042 18.47 5500
3 173752942 179284891 8.02 1300
5 171792682 180625733 18.64 2613
17 74799181 78639702 8.85 1023
18 4458642 11750915 17.58 2693
X 131769934 139569333 10.25 925

GEDMatch 
One to One comparison at the default settings of 500 SNPs minimum 7cM segments
Comparing Kit A and Kit B
ChrStart LocationEnd LocationCentimorgans (cM)SNPs
190,080,689107,508,90715.54,344
250,728,18571,670,51117.95,333
3173,574,411179,657,3938.61,369
5171,696,763180,623,54320.52,515
1774,702,72278,637,19810.81,013
184,326,19111,866,61328.12,716
2219,337,48523,815,8029.7836
Largest segment = 28.1 cM
Total of segments > 7 cM = 111.1 cM
7 matching segments
Estimated number of generations to MRCA = 3.5

672062 SNPs used for this comparison.


MyHeritage
This maternal cousin does show up on the MyHeritage match lists for my two maternal aunts, both 
sharing 5.5%, 395cMs total, largest 63cMs, one with 14 segments, the other with 18.
But nowhere to be found on my match list, nor I on hers.

Looking at the FTDNA Chromosome Browser picture for my 2nd cousin compared to myself and the maternal aunts clearly shows at least three segments where I match at least one of the aunts (chr. 1,2,5) at which spots those matches total about 52cMs, well above what I'd consider a match from MyHeritage


Has been logged with MyHeritage Support for their scientists to take a look